Can we accurately predict phenotype from genotype in polygenic traits?

Question: Can we accurately predict phenotype from genotype in polygenic traits?
- Keywords:
  predict
Asked by them20fen to Sally, Mmboyi, Mike, Michael, Jacinta, Gliday, Elkana, Edna, Arnold on 17 Jul 2025.
- Michael Kimwele answered on 17 Jul 2025:
  
  While it’s possible to predict some polygenic traits from genotype with reasonable accuracy, particularly for highly heritable traits, complete and accurate prediction is generally not possible due to the complex interplay of multiple genes and environmental factors.

Question: Can we accurately predict phenotype from genotype in polygenic traits?