• Question: Evaluate the consequences of an underproduction of thyroid hormones during childhood

    Asked by Dr. Levis Mweri to Sally, Mmboyi, Mike, Michael, Jacinta, Gliday, Elkana, Edna, Arnold on 17 Jul 2025.
    • Photo: Michael Kimwele

      Michael Kimwele answered on 17 Jul 2025:


      An underproduction of thyroid hormones during childhood, a condition known as congenital hypothyroidism or juvenile hypothyroidism, can lead to serious and often irreversible consequences if left untreated. These hormones are crucial for normal growth, brain development, and metabolism. Insufficient levels can result in stunted physical growth (dwarfism), delayed puberty, and intellectual disabilities due to impaired brain maturation. Children may also experience fatigue, weight gain, dry skin, constipation, and poor academic performance. Early detection and treatment with thyroid hormone replacement are essential to prevent long-term developmental delays and ensure healthy physical and cognitive growth.

    • Photo: Jacinta Nzilani

      Jacinta Nzilani answered on 17 Jul 2025:


      Hey! 👋

      What happens if a child doesn’t produce enough thyroid hormones?

      When a child doesn’t produce enough thyroid hormones, they develop a condition known as hypothyroidism. This occurs when the thyroid gland located in the neck fails to make sufficient thyroid hormones, which are essential for controlling metabolism, growth, and many other bodily functions.

      Causes:
      Hypothyroidism in children can result from several causes:

      Autoimmune disorders such as Hashimoto’s disease, where the immune system mistakenly attacks the thyroid gland.

      Pituitary gland problems, since it regulates thyroid function.

      Certain medications.

      Sometimes, the cause remains unknown.

      Congenital Hypothyroidism:
      In newborns and children, congenital hypothyroidism (present at birth) can lead to:

      Slowed growth

      Developmental delays if left untreated

      Common Symptoms:
      Puffy face

      Swollen hands and feet

      Poor muscle tone

      Sluggishness or excessive sleepiness

      Constipation

      Fatigue

      Dry, itchy scalp

      Dry, coarse skin

      If you’re interested in more detailed information, you can check out the article on Pediatric Endocrinology & Diabetes Care from Johns Hopkins Medicine.

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